Physical examination revealed the presence of a pink salmonpatch. To report clinical, histopathological and molecular features of salmon patchlike conjunctival lesions in paediatric and adolescent patients, and discuss management of these patients and outcome. The lesions of diffuse large b cell lymphoma may have a grayish coloration. Purpose we describe a rare case of a complex choristoma appearing as a salmonpatch lesion in the nasal conjunctiva. This cyst often looks like a clear bubble on the surface of the eye. The etiology is unknown but is thought to be due to chronic inflammation. Paediatric and adolescent elevated conjunctival lesions in. We report a 70yearold man with a salmon patch conjunctival mass diagnosed as multiple myeloma. A glistening salmon patch lesion in the bulbar conjunctiva. Features such as rapid growth, invasion of surrounding tissues, ulceration and presence of feeder vessels support a diagnosis of lymphoma. An excisional biopsy was performed utilizing a notouch technique, given the possibility of a malignant lesion, with removal of the conjunctival tumor and placement of an amniotic membrane graft. Classification, diagnosis, and management of conjunctival lymphoma. If there is a conjunctival component, or if the lesion extends onto the globe, it can be seen as a salmon patch lesion on or under the conjunctiva as shown above. Conjunctival lymphoma is an ocular surface tumor that usually appears as a painless, salmonpink, fleshy patch.
Download scientific diagram a, clinical photograph of the classical salmonpatch conjunctival lymphoma. Surgical biopsies of the salmon patch conjunctival mass and bone marrow, as well as. The biopsy confirmed lymphoma conjunctival lymphoma in the right eye of a patient. Bulbar involvement is more common, usually more easily recognized, and is associated with a better prognosis than malt lymphoma of the palpebral conjunctiva. Examination of the lower mediobulbar and forniceal conjunctiva of the left eye of a 37yearold female patient showed a typical salmon pink patch. Although it generally has a smooth surface, it can also appear as a multinodular lesion or as follicular conjunctivitis fig. A, clinical photograph of the classical salmonpatch conjunctival. The lesion often has a color similar to salmon, hence the term salmon patch. The clinical presentation of conjunctival malt lymphomas is non. These lesions are fleshy and often originate the fornix or adjacent to the limbus. The photograph shows a pink raised conjunctival lesion with an. An unusual presentation of pediatric conjunctival mucosa.
Classification, diagnosis, and management of conjunctival. Slit lamp image of right eye with salmon patch conjunctival lesion in the superior temporal conjunctiva. Diagnosis and treatment of conjunctival lymphoma american. While benign, complex choristomas are grossly indistinguishable from malignant. It usually presents as a salmonpink nodular patch involving the bulbar conjunctiva. Conjunctival malt lymphoma characteristically manifests as a painless fleshycoloured salmonpatch lesion arising from the fornix. Conjunctival malt lymphoma characteristically manifests as a painless fleshycoloured salmonpatch lesion arising from the fornix 6. These lesions are usually primary extranodal bcell neoplasms, although 10 to 30.
In this report, the salmon patch conjunctival mass was an initial manifestation of multiple myeloma, but based on the results of bone marrow biopsy, and hematologic and image. Conjunctival malt lymphoma characteristically manifests as a painless fleshy coloured salmonpatch lesion arising from the fornix 6. A complex choristoma presenting as a salmon patch lesion. On exam, conjunctival lesions are classically described as salmon patch fleshy lesions. Eye examination revealed a salmoncolored raised lesion involving supranasal bulbar conjunctiva extending to superior fornix of the left eye. The differential diagnosis for an elevated salmoncolored conjunctival patch most commonly includes benign lymphoid hyperplasia and conjunctival lymphoma.
Distinct clinical clues may be suggestive of a subtype, such as emzl demonstrating a mobile, nonlobulated salmonpink patch or follicular lymphoma demonstrating a multinodular appearance. To report clinical, histopathological and molecular features of salmon patchlike conjunctival lesions in paediatric and adolescent patients, and discuss management of. Known causes of conjunctival salmon patches include lymphoma, amyloidosis, sarcoidosis, relapsing polychondritis, leukemia, and benign reactive lymphoid hyperplasia. It commonly occurs in the forniceal conjunctiva, appearing. The patient population usually includes young to middle aged adults and the presenting sign is usually chronic redness 3.
1279 401 26 33 164 876 940 598 559 1403 1450 1042 492 556 1483 714 1340 701 724 322 1393 100 375 412 1118 1124 345 181 422 486 536